Protein biochemistry also performs
biophysical analytics of recombinant
therapeutic proteins, which includes
(1) SPR (Biacore T200) for label-free
characterization of biomolecular
interactions, (2) ELISA / AlphaLISA /
AlphaScreen for biomolecular interaction
studies in microplate format, and (3)
capillary electrophoresis (Sciex PA800
Plus) for determination of purity,
heterogeneity by CE-SDS and charge
variants by CZE or hi-res cIEF (ICE). Our
expertise and experience span different
classes of protein biotherapeutics
including mAbs, insulins, GPCRs as well
as synthetic peptides.